A Layperson's View:

This is a layperson's view of how statins will affect the other processes in the body that rely on the cholesterol metabolic pathway.

Cholesterol is an essential component of every cell in the body. Removing it, or as shown in the diagram that you can see by clicking in the link, stopping cholesterol from forming is a very bad thing.

We are told that statin therapies are helpful and that lowering your cholesterol is a good thing. Trace the pathway of cholesterol metabolism (in the diagram... by following the direction of the arrows) in the body and see how early in the manufacture of cholesterol, statins interfere with an essential chain of life.

This subject material involves complex biochemical interactions and the list of bullet points will give you some sense of the harm caused by statins. Clicking on the relevant links will take you to pages that discuss the biochemistry in a little more detail.

A diagram of a cholesterol factory

The key points to remember are...

Statins lower your cholesterol

Statins inhibit the production of Cholesterol

Statins inhibit the production of Heme A

Statins inhibit the production of Dolichol

Statins inhibit the production of Ubiqinone

Statins inhibit the production of Prenylated Proteins

To find out more follow the link to Simple Biochemistry

Note: Thanks are due to Mr Brian Clark, for his hard work and his
excellent contributions to this complete section of the web-site




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